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      Methyl-β-cyclodextrin研究進(jìn)展
      
                
      
                發(fā)布日期：2017-10-30                                                  瀏覽次數(shù)：0
                
      

      核心提示：a href=https://www.medchemexpress.com/Methyl-_beta_-cyclodextrin.htmlMethyl--cyclodextrin/a產(chǎn)品描述：Methyl--cyclodextri
                                      
      
    
    
        
      
            <a   href="https://www.medchemexpress.com/Methyl-_beta_-cyclodextrin.html">Methyl-β-cyclodextrin</a>產(chǎn)品描述：Methyl-β-cyclodextrin,   a cyclic heptasaccharide, is an effective agent for the depletion of   cholesterol from cells; also inhibits PEL cell growth with an   <b>IC<sub>50</sub></b> of 3.33-4.23 mM.
      
            
      
            IC50 & Target: IC50: 3.33-4.23 mM (PEL cell   growth)<sup>[1]</sup>
      
            
      
            <i><b>In Vitro:</b></i> Cyclodextrins are a family   of cyclic oligosaccharides with a hydrophilic outer surface and a lipophilic   central cavity. Cyclodextrins molecules are relatively large with a number of   hydrogen donors and acceptors and, thus in general, they do not permeate lipophilic   membranes. In the pharmaceutical industry, cyclodextrins have mainly been   used as complexing agents to increase aqueous solubility of poorly soluble   drugs and to increase their bioavailability and stability. Cyclodextrins are   used in pharmaceutical applications for numerous purposes, including   improving the bioavailability of drugs<sup>[2]</sup>.   Methyl-β-cyclodextrin quickly induces caspase-dependent apoptosis in PEL   cells via cholesterol dep<br><br>
      
            <br>
      
            <span style="outline: 0.0px;line-height: 22.0px;color:   rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial ,   sans-serif;font-size: 11.818182px;background-color:   rgb(251,251,251);">公司介紹：MedChemExpress(MCE)專注于各種抑制劑、激動(dòng)劑、API及化合物庫(kù)，總部位于美國(guó)新澤西，分別在瑞典和上海設(shè)有歐洲區(qū)子公司和亞洲區(qū)總代理，營(yíng)銷網(wǎng)點(diǎn)遍及全球20多個(gè)國(guó)家地區(qū)。MCE經(jīng)過多年努力已成為全球生物活性小分子領(lǐng)域的一流供應(yīng)商，   產(chǎn)品涵蓋癌癥、神經(jīng)科學(xué)、抗感染、表觀遺傳學(xué)等20個(gè)熱門研究領(lǐng)域，PI3K、MAPK等近千個(gè)細(xì)分靶點(diǎn)，超過4000個(gè)活性小分子化合物現(xiàn)貨，以及GPCR、API、離子通道等超過20種不同類型的化合物庫(kù)，同時(shí)提供從毫克到千克的專業(yè)定制合成服務(wù)。</span>
      
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            <span style="outline: 0.0px;line-height: 22.0px;color:   rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial ,   sans-serif;font-size: 11.818182px;background-color:   rgb(251,251,251);">大量產(chǎn)品提供免費(fèi)試用裝；</span>
      
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            已為全球多個(gè)知名企業(yè)、院校構(gòu)建各種定制型化合物庫(kù)。</span><br><br>產(chǎn)品鏈接：<a   href="http://www.medchemexpress.cn/methyl-_beta_-cyclodextrin.html">www.medchemexpress.cn/methyl-_beta_-cyclodextrin.html</a><br><br></span><img   style="width: 600.0px;height: 310.0px;" 
      
            
      
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