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      Tulathromycin A研究進展
      
                
      
                發(fā)布日期：2017-10-31                                                  瀏覽次數(shù)：0
                
      

      核心提示：a href=https://www.medchemexpress.com/Tulathromycin-A.htmlTulathromycin A/a產(chǎn)品描述：Tulathromycin A is a macrolide anti
                                      
      
    
    
        
      
            <a   href="https://www.medchemexpress.com/Tulathromycin-A.html">Tulathromycin   A</a>產(chǎn)品描述：Tulathromycin A is a macrolide antibiotic.IC50 Value: 1   microg/ml (MIC90 for Pasteurella multocida) [2]Target: Antibacterialin vitro:   Two highly pathogenic strains of M. bovis (with minimum inhibitory   concentration values for tulathromycin of 1 and >64 microg/ml) were   inoculated into 145 calves. Four days after inoculation, calves with clinical   BRD were treated subcutaneously with saline or tulathromycin (2.5 mg/kg).   Compared with saline, BRD-related withdrawals, peak rectal temperatures, and   lung lesion scores were significantly lower for tulathromycin-treated calves   (P < .01). Tulathromycin was highly effective in the treatment of BRD due   to M. bovis in calves regardless of the minimum inhibitory concentration of   the challenge strain (1 or >64 microg/ml) [1]. The lowest concentrations   inhibiting the growth of 90% of isolates (MIC90) for tulathromycin were 2   microg/ml for Mannheimia (Pasteurella) haemolytica, 1 microg/ml for   Pasteurella multocida (bovine), and 2 microg/ml for   P<br><br><br><span style="outline:   0.0px;line-height: 22.0px;color: rgb(62,62,62);font-family: "Helvetica   Neue" , Helvetica , Arial , sans-serif;font-size:   11.818182px;background-color:   rgb(251,251,251);">公司介紹：MedChemExpress(MCE)專注于各種抑制劑、激動劑、API及化合物庫，總部位于美國新澤西，分別在瑞典和上海設(shè)有歐洲區(qū)子公司和亞洲區(qū)總代理，營銷網(wǎng)點遍及全球20多個國家地區(qū)。MCE經(jīng)過多年努力已成為全球生物活性小分子領(lǐng)域的一流供應(yīng)商，   產(chǎn)品涵蓋癌癥、神經(jīng)科學(xué)、抗感染、表觀遺傳學(xué)等20個熱門研究領(lǐng)域，PI3K、MAPK等近千個細分靶點，超過4000個活性小分子化合物現(xiàn)貨，以及GPCR、API、離子通道等超過20種不同類型的化合物庫，同時提供從毫克到千克的專業(yè)定制合成服務(wù)。</span><br   style="color: rgb(62,62,62);font-family: "Helvetica Neue" ,   Helvetica , Arial , sans-serif;font-size: 11.818182px;line-height:   22.0px;background-color: rgb(251,251,251);"><span   style="outline: 0.0px;line-height: 22.0px;color:   rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial ,   sans-serif;font-size: 11.818182px;background-color: rgb(251,251,251);">MCE   對每批產(chǎn)品都進行嚴格的LCMS和NMR檢驗，其產(chǎn)品已被全球近萬名客戶廣泛使用并發(fā)表大量文章、專利；</span><br   style="color: rgb(62,62,62);font-family: "Helvetica Neue" ,   Helvetica , Arial , sans-serif;font-size: 11.818182px;line-height:   22.0px;background-color: rgb(251,251,251);"><span   style="outline: 0.0px;line-height: 22.0px;color:   rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial ,   sans-serif;font-size: 11.818182px;background-color:   rgb(251,251,251);">MCE 定期增加各領(lǐng)域熱門抑制劑、激動劑，不斷擴增已有化合物庫，以滿足最新的科研需求；</span><br   style="color: rgb(62,62,62);font-family: "Helvetica Neue" ,   Helvetica , Arial , sans-serif;font-size: 11.818182px;line-height:   22.0px;background-color: rgb(251,251,251);"><span style="outline:   0.0px;line-height: 22.0px;color: rgb(62,62,62);font-family: "Helvetica   Neue" , Helvetica , Arial , sans-serif;font-size:   11.818182px;background-color:   rgb(251,251,251);">數(shù)千種產(chǎn)品在上海有充足備貨，24-48小時內(nèi)送達客戶；</span><br   style="color: rgb(62,62,62);font-family: "Helvetica Neue" ,   Helvetica , Arial , sans-serif;font-size: 11.818182px;line-height:   22.0px;background-color: rgb(251,251,251);"><span   style="outline: 0.0px;line-height: 22.0px;color:   rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial ,   sans-serif;font-size: 11.818182px;background-color:   rgb(251,251,251);">大量產(chǎn)品提供免費試用裝；</span><span   style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);font-family:   "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size:   11.818182px;background-color:   rgb(251,251,251);">已為全球多個知名企業(yè)、院校構(gòu)建各種定制型化合物庫。</span><br><br>產(chǎn)品鏈接：<a   href="http://www.medchemexpress.cn/tulathromycin-a.html">www.medchemexpress.cn/tulathromycin-a.html</a><br><br></span><img   style="width: 600.0px;height: 310.0px;"   src="http://img.dxycdn.com/trademd/upload/userfiles/image/2014/08/A1408605159png_small.jpg"   alt="">
        
      
          

      

      
                                                
       
      
                

      


      

       
      

      

      
    
    
       
      

        
      

      

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