欧美人妻精品区三区|无码免费特级毛片|久久伊人中文无码|亚洲欧洲免费在线播放

<optgroup id="khvqs"><em id="khvqs"></em></optgroup>

    • <span id="khvqs"><sup id="khvqs"></sup></span>
      <optgroup id="khvqs"></optgroup>
      <acronym id="khvqs"><sup id="khvqs"></sup></acronym>
      <track id="khvqs"><i id="khvqs"></i></track>
    1. 






      

      
        
      
            
      
                
      
                當(dāng)前位置: 首頁 » 資訊 » 行業(yè)動態(tài) » 正文
                
      

      YM-58483研究進(jìn)展
      
                
      
                發(fā)布日期：2017-10-27                                                  瀏覽次數(shù)：0
                
      

      核心提示：a href=https://www.medchemexpress.com/YM-58483.htmlYM-58483/a產(chǎn)品描述：YM-58483 is the first selective and potent inhibi
                                      
      
    
    
        
      
            <a   href="https://www.medchemexpress.com/YM-58483.html">YM-58483</a>產(chǎn)品描述：YM-58483   is the first selective and potent inhibitor of <b>CRAC   channels</b> and subsequent Ca<sup>2+</sup> signals.
      
            
      
            <i><b>In Vitro:</b></i> YM-58483 can decrease the   levels of P-ERK and P-CREB, without affecting the expression of CD11b and   GFAP. YM-58483 also inhibits the release of spinal cord IL-1β,   TNF-α, and PGE2<sup>[1]</sup>. YM-58483 and cyclosporine A   inhibits T cell proliferation in a one-way mixed lymphocyte reaction (mLR)   with IC<sub>50</sub> values of 330 and 12.7 nM,   respectively<sup>[2]</sup>. YM-58483 inhibits DNP antigen-induced   histamine release from and leukotrienes (LTs) production in IgE-primed   RBL-2H3 cells, a rat basophilic leukemia cell line, with   IC<sub>50</sub> values of 460 and 310 nM, respectively. YM-58483   also inhibits phytohemagglutinin-P (PHA)-stimulated IL-5 and IL-13 production   in human peripheral blood cells with IC<sub>50</sub> values of   125 and 148 nM, respectively, which is approximately 5 times less potent than   prednisolone<sup>[3]</sup>. YM-584<br><br>
      
            <br>
      
            <span style="outline: 0.0px;line-height: 22.0px;color:   rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial ,   sans-serif;font-size: 11.818182px;background-color:   rgb(251,251,251);">公司介紹：MedChemExpress(MCE)專注于各種抑制劑、激動劑、API及化合物庫，總部位于美國新澤西，分別在瑞典和上海設(shè)有歐洲區(qū)子公司和亞洲區(qū)總代理，營銷網(wǎng)點(diǎn)遍及全球20多個國家地區(qū)。MCE經(jīng)過多年努力已成為全球生物活性小分子領(lǐng)域的一流供應(yīng)商，   產(chǎn)品涵蓋癌癥、神經(jīng)科學(xué)、抗感染、表觀遺傳學(xué)等20個熱門研究領(lǐng)域，PI3K、MAPK等近千個細(xì)分靶點(diǎn)，超過4000個活性小分子化合物現(xiàn)貨，以及GPCR、API、離子通道等超過20種不同類型的化合物庫，同時提供從毫克到千克的專業(yè)定制合成服務(wù)。</span>
      
            <br style="color: rgb(62,62,62);font-family: "Helvetica   Neue" , Helvetica , Arial , sans-serif;font-size:   11.818182px;line-height: 22.0px;background-color:   rgb(251,251,251);">
      
            <span style="outline: 0.0px;line-height: 22.0px;color:   rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial ,   sans-serif;font-size: 11.818182px;background-color:   rgb(251,251,251);">MCE   對每批產(chǎn)品都進(jìn)行嚴(yán)格的LCMS和NMR檢驗(yàn)，其產(chǎn)品已被全球近萬名客戶廣泛使用并發(fā)表大量文章、專利；</span>
      
            <br style="color: rgb(62,62,62);font-family: "Helvetica   Neue" , Helvetica , Arial , sans-serif;font-size:   11.818182px;line-height: 22.0px;background-color:   rgb(251,251,251);">
      
            <span style="outline: 0.0px;line-height: 22.0px;color:   rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial ,   sans-serif;font-size: 11.818182px;background-color:   rgb(251,251,251);">MCE   定期增加各領(lǐng)域熱門抑制劑、激動劑，不斷擴(kuò)增已有化合物庫，以滿足最新的科研需求；</span>
      
            <br style="color: rgb(62,62,62);font-family: "Helvetica   Neue" , Helvetica , Arial , sans-serif;font-size:   11.818182px;line-height: 22.0px;background-color:   rgb(251,251,251);">
      
            <span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);font-family:   "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size:   11.818182px;background-color:   rgb(251,251,251);">數(shù)千種產(chǎn)品在上海有充足備貨，24-48小時內(nèi)送達(dá)客戶；</span>
      
            <br style="color: rgb(62,62,62);font-family: "Helvetica   Neue" , Helvetica , Arial , sans-serif;font-size:   11.818182px;line-height: 22.0px;background-color:   rgb(251,251,251);">
      
            <span style="outline: 0.0px;line-height: 22.0px;color:   rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial ,   sans-serif;font-size: 11.818182px;background-color:   rgb(251,251,251);">大量產(chǎn)品提供免費(fèi)試用裝；</span>
      
            <span style="outline: 0.0px;line-height: 22.0px;color:   rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial ,   sans-serif;font-size: 11.818182px;background-color:   rgb(251,251,251);">
      
            已為全球多個知名企業(yè)、院校構(gòu)建各種定制型化合物庫。</span><br><br>產(chǎn)品鏈接：<a   href="http://www.medchemexpress.cn/ym-58483.html">www.medchemexpress.cn/ym-58483.html</a><br><br></span><img   style="width: 600.0px;height: 310.0px;" 
      
            
      
            src="http://img.dxycdn.com/trademd/upload/userfiles/image/2014/08/A1408605159png_small.jpg"   
      
            
      
            alt="">      		
        
      
          

      

      
                                                
       
      
                

      


      

       
      

      

      
    
    
       
      

        
      

      

?