26833-85-2：產(chǎn)品說明書
<a href="https://www.medchemexpress.com/Harringtonine.html">Harringtonine</a>產(chǎn)品描述：Harringtonine, a natural <i>Cephalotaxus</i> alkaloid, is an inhibitor of protein synthesis.<i><b>In Vitro:</b></i> Harringtonine inhibits the elongation phase of translation by preventing substrate binding to the acceptor site on the 60-S ribosome subunit and therefore block aminoacyl-tRNA binding and peptide bond formation<sup>[1]</sup>. Harringtonine displays potent inhibition of Chikungunya virus infection with an EC<sub>50</sub> of 0.24 μM. Harringtonine could inhibit other alphaviruses<sup>[2]</sup>. Harringtonine inhibits the growth of human myeloid leukemia cells <i>in vitro</i> at low concentrations. The mechanism of the antitumor action of harringtonine is considered to be an effect on protein synthesis and is characterized by breakdown of polysomes to monosomes<sup>[3]</sup>. <br /><br /><br /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">公司介紹：MedChemExpress(MCE)專注于各種抑制劑、激動劑、API及化合物庫，總部位于美國新澤西，分別在瑞典和上海設(shè)有歐洲區(qū)子公司和亞洲區(qū)總代理，營銷網(wǎng)點遍及全球20多個國家地區(qū)。MCE經(jīng)過多年努力已成為全球生物活性小分子領(lǐng)域的一流供應(yīng)商， 產(chǎn)品涵蓋癌癥、神經(jīng)科學(xué)、抗感染、表觀遺傳學(xué)等20個熱門研究領(lǐng)域，PI3K、MAPK等近千個細(xì)分靶點，超過4000個活性小分子化合物現(xiàn)貨，以及GPCR、API、離子通道等超過20種不同類型的化合物庫，同時提供從毫克到千克的專業(yè)定制合成服務(wù)。</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">MCE 對每批產(chǎn)品都進(jìn)行嚴(yán)格的LCMS和NMR檢驗，其產(chǎn)品已被全球近萬名客戶廣泛使用并發(fā)表大量文章、專利；</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">MCE 定期增加各領(lǐng)域熱門抑制劑、激動劑，不斷擴(kuò)增已有化合物庫，以滿足最新的科研需求；</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">數(shù)千種產(chǎn)品在上海有充足備貨，24-48小時內(nèi)送達(dá)客戶；</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">大量產(chǎn)品提供免費試用裝；</span><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">已為全球多個知名企業(yè)、院校構(gòu)建各種定制型化合物庫。</span><br /><br />產(chǎn)品鏈接：<a href="http://www.medchemexpress.cn/harringtonine.html">www.medchemexpress.cn/harringtonine.html</a><br /><br /><img alt="" src="http://img.dxycdn.com/trademd/upload/userfiles/image/2014/08/A1408605159png_small.jpg" style="width: 600.0px;height: 310.0px;" /> </div>
<a href="https://www.medchemexpress.com/Harringtonine.html">Harringtonine</a>產(chǎn)品描述：Harringtonine, a natural <i>Cephalotaxus</i> alkaloid, is an inhibitor of protein synthesis.<i><b>In Vitro:</b></i> Harringtonine inhibits the elongation phase of translation by preventing substrate binding to the acceptor site on the 60-S ribosome subunit and therefore block aminoacyl-tRNA binding and peptide bond formation<sup>[1]</sup>. Harringtonine displays potent inhibition of Chikungunya virus infection with an EC<sub>50</sub> of 0.24 μM. Harringtonine could inhibit other alphaviruses<sup>[2]</sup>. Harringtonine inhibits the growth of human myeloid leukemia cells <i>in vitro</i> at low concentrations. The mechanism of the antitumor action of harringtonine is considered to be an effect on protein synthesis and is characterized by breakdown of polysomes to monosomes<sup>[3]</sup>. <br /><br /><br /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">公司介紹：MedChemExpress(MCE)專注于各種抑制劑、激動劑、API及化合物庫，總部位于美國新澤西，分別在瑞典和上海設(shè)有歐洲區(qū)子公司和亞洲區(qū)總代理，營銷網(wǎng)點遍及全球20多個國家地區(qū)。MCE經(jīng)過多年努力已成為全球生物活性小分子領(lǐng)域的一流供應(yīng)商， 產(chǎn)品涵蓋癌癥、神經(jīng)科學(xué)、抗感染、表觀遺傳學(xué)等20個熱門研究領(lǐng)域，PI3K、MAPK等近千個細(xì)分靶點，超過4000個活性小分子化合物現(xiàn)貨，以及GPCR、API、離子通道等超過20種不同類型的化合物庫，同時提供從毫克到千克的專業(yè)定制合成服務(wù)。</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">MCE 對每批產(chǎn)品都進(jìn)行嚴(yán)格的LCMS和NMR檢驗，其產(chǎn)品已被全球近萬名客戶廣泛使用并發(fā)表大量文章、專利；</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">MCE 定期增加各領(lǐng)域熱門抑制劑、激動劑，不斷擴(kuò)增已有化合物庫，以滿足最新的科研需求；</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">數(shù)千種產(chǎn)品在上海有充足備貨，24-48小時內(nèi)送達(dá)客戶；</span><br style="color: rgb(62,62,62);" /><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">大量產(chǎn)品提供免費試用裝；</span><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);">已為全球多個知名企業(yè)、院校構(gòu)建各種定制型化合物庫。</span><br /><br />產(chǎn)品鏈接：<a href="http://www.medchemexpress.cn/harringtonine.html">www.medchemexpress.cn/harringtonine.html</a><br /><br /><img alt="" src="http://img.dxycdn.com/trademd/upload/userfiles/image/2014/08/A1408605159png_small.jpg" style="width: 600.0px;height: 310.0px;" /> </div>
110102000668（1）號